Molecular block-matching method for gel image analysis

  1. Inventores/as:
  2. Alejandro Pazos Sierra
  3. Julián Dorado De la Calle
  4. Francisco Blanco García
  5. Javier Pereira Loureiro
  6. Juan Ramón Rabuñal Dopico
  7. Cristina Ruiz Romero
  8. José Antonio Seoane Fernández
  9. Ana María Freire Veiga
  10. Enrique Fernández Blanco
  11. Alvaro Rodriguez Tajes
  12. Carlos Fernandez Lozano
  13. Ana Belén Porto Pazos
  14. Cristian Robert Munteanu
  1. Universidade da Coruña
    info
    Universidade da Coruña

    La Coruña, España

    Localización geográfica de la organización Universidade da Coruña
  2. Servizo Galego de Saúde
    info
    Servizo Galego de Saúde

    Coruna, España

    Localización geográfica de la organización Servizo Galego de Saúde
US
Publicación principal:

US8897536B2 (25-11-2014)

Otras Publicaciones:

US8897536B2 (25-11-2014)

US20130108140A1 (02-05-2013)

Solicitudes:

US8897536B2 (24-04-2011)

Resumen

A method for analysis of 2-D gel images obtained using electrophoresis. More particularly, a molecular block-matching method for establishing the correspondence between protein spots in a diagnostic-test image and protein spots in a reference image. Individual protein spot matching is performed, thereby removing the need for alignment of the entire reference and test images and permitting automatic labeling of individual protein spots. The method for analysis of 2-D gel images is fully automated, thus making it ideally suited for protein information retrieval systems.