Tratamiento del paciente alcohólico y del síndrome de abstinencia alcohólica

  1. M. Bermúdez Ramos 1
  2. E. Otero Antón 1
  3. S. Tomé 1
  1. 1 Complexo Hospitalario Universitario de Santiago
    info

    Complexo Hospitalario Universitario de Santiago

    Santiago de Compostela, España

    ROR https://ror.org/00mpdg388

Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2016

Issue Title: Enfermedades del aparato digestivo (X) Enfermedades hepáticas

Series: 12

Issue: 10

Pages: 583-590

Type: Article

DOI: 10.1016/J.MED.2016.05.007 DIALNET GOOGLE SCHOLAR

More publications in: Medicine: Programa de Formación Médica Continuada Acreditado

Sustainable development goals

Abstract

Introduction Alcohol consumption is responsible for an overall mortality rate of 6%. Alcohol use disorders The alcohol abuse as well as alcohol dependence is now involved in a broader concept known of AUD (Alcohol Use Disorders). While acute alcohol produces a depressant effect of the central nervous system, chronic use produces an inhibition of the excitatory GABA system and superregulacion of glutamate, dopamine as well as an increased activation of the opioid system. Alcohol withdrawal syndrome Alcohol withdrawal syndrome occurs after cessation of chronic alcohol use and is the main complication of alcohol dependence. Treatment The most used drugs are benzodiazepines (GABA stimulators) for the wide therapeutic window, having no cross-tolerance with alcohol and antidote available in case of overdose. In chronic treatment should evaluate all modulating drugs of neurotransmitters involved.

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Data source: Dialnet