Restricción del crecimiento extrauterino en recién nacidos de menos de 1.500 gramos de peso al nacer

  1. Alejandro Avila-Alvarez 23
  2. Alfonso Solar Boga 12
  3. Carmen Bermúdez-Hormigo 23
  4. Jesús Fuentes Carballa 3
  1. 1 Unidad de Gastroenterología, Hepatología y Nutrición pediátrica, Servicio de Pediatría, Complexo Hospitalario Universitario de A Coruña, Sergas
  2. 2 Departamento de Pediatría, Universidade de Santiago de Compostela
  3. 3 Unidad de Neonatología, Servicio de Pediatría. Complexo Hospitalario Universitario de A Coruña, Sergas
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Revista:
Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría ( AEP )

ISSN: 1695-4033,  1696-4608

Ano de publicación: 2018

Volume: 89

Número: 6

Páxinas: 325-332

Tipo: Artigo

DOI: 10.1016/J.ANPEDI.2018.02.004 PMID: 29650428 SCOPUS: 2-s2.0-85045112857 DIALNET GOOGLE SCHOLAR lock_openAcceso aberto editor

Outras publicacións en: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría ( AEP )

Resumo

Introduction: Growth restriction in preterm infants has been related to a poor neurodevelopment outcome. Objectives: To define the incidence of postnatal growth restriction in premature babies ≤ 1,500 grams and to detect related clinical or biochemical markers. Methods: Retrospective longitudinal observational study. Multivariate linear regression models were used to determine variables that can predict the change in weight z-score during admission. Results: The study included 130 patients with a mean birthweight of 1,161 ± 251 grams and a gestational age of 29.9 ± 2.5 weeks. At hospital discharge, 59.2% had a weight below P10.During admission, the z-scores of weight and length decreased by -0.85 ± 0.79 and –1.09 ± 0.65, respectively.The largest decrease in z-score occurred during NICU admission, with a weight gain rate of 6.6 ± 8.8 g/Kg/day, after which growth acceleration took place (16.7 ± 3.8 g/Kg/day), but was insufficient to catch-up.Higher levels of urea were negatively correlated with the change in the z-score of weight (P <.001), and a weight < P10 at birth positively correlated (P =.013). Conclusions: More than half of newborns ≤ 1,500 grams have a weight at discharge of < P10. This growth restriction occurs during NICU admission, and affects low birth weight infants less frequently.Urea levels correlate negatively with weight gain, which requires further study of the relationship between growth and the protein compartment.

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Fonte de datos: Dialnet