Calidad de vida en pacientes con melanoma de coroides

  1. C. Blanco-Rivera
  2. C. Capeáns-Tomé
  3. X.L. Otero-Cepeda
Journal:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2008

Volume: 83

Issue: 5

Pages: 301-306

Type: Article

DOI: 10.4321/S0365-66912008000500005 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Archivos de la Sociedad Española de Oftalmologia

Abstract

Purpose: To determine whether iodine 125 brachytherapy or enucleation is better for quality of life in patients treated for choroidal melanoma. Patients and methods: Sixty-five patients with choroidal melanoma were treated with a modified version of VF-14 iodine 125 brachytherapy, enucleation or both. Results of this treatment were then statistically analyzed. Results: Statistically significant differences were found between visual acuity in the affected eye and binocular vision (initial and final), with an important decline after the treatment. The global medial score in the VF questionnaire decreased in a statistically significant manner after the treatment. Conclusion: We can confirm that patients treated with brachytherapy had better health-related quality of life than those who had their eye enucleated and were more likely to have higher (better) scores on the VF questionnaire items. On the other hand, the binocular vision and time after the treatment correlated with the quality of life in long-term follow-up.

Bibliographic References

  • Cruickshanks, KJ, Fryback, DG, Nondahl, DM, Robinson, N, Keesey, U, Dalton, DS. (1999). Treatment choice and quality of life in patients with choroidal melanoma. Arch Ophthalmol. 117. 461-467
  • Capeans, C. (1993). Melanomas de la úvea. Sociedad Española de Oftalmología. Madrid.
  • Singh, AD, Rennie, IG, Kivela, T, Seregard, S, Grossniklaus, H. (2004). The Zimmerman-McLean-Foster hypothesis: 25 years later. Br J Ophthalmol. 88. 962-967
  • (1998). The Collaborative Ocular Melanoma Study (COMS) randomized trial of pre- enucleation radiation of large choroidal melanoma II: initial mortality findings. COMS report no 10. Am J Ophthalmol. 125. 779-796
  • Diener-West, M, Earle, JD, Fine, SL, Hawkins, BS, Moy, CS, Reynolds, SM. (2001). The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma, III: initial mortality findings. COMS Report No. 18. Arch Ophthalmol. 119. 969-982
  • Reimer, J, Esser, J, Fleiss, A, Hessel, A, Anastassiou, G, Krausz, M. (2003). Quality of life in patients with malignant choroidal melanoma after radiotherapy. Graefes Arch Clin Exp Ophthalmol. 241. 371-377
  • Melia, MB, Moy, SC, McCaffrey, L. (1999). Quality of life in patients wiht choroidal melanoma: a pilot study. Ophthalmic Epidemiol. 6. 19-28
  • (1999). Quality of life assessment in the collaborative ocular melanoma study: desing and methods: COMS-QOLS Report No. 1. COMS Quality of Life Study Group. Ophthalmic Epidemiol. 6. 5-17
  • Melia, M, Moy, CS, Reynolds, SM, Cella, D, Murray, TG, Hovland, KR. (2003). Development and validation of disease- specific measures for choroidal melanoma: COMS-QOLS report No. 2. Arch Ophthalmol. 121. 1010-1020
  • Melia, M, Moy, CS, Reynolds, SM, Hayman, JA, Murray, TG, Hovland, KR. (2006). Quality of life after iodine 125 brachytherapy vs enucleation for choroidal melanoma: 5-year results from the Collaborative Ocular Study: COMS QOLS Report No 3. Arch Ophthalmol. 124. 226-238
  • Casado, J, González, N, Moraleda, S, Orueta, R, Carmona, J, Gómez-Calcerrada, RM. (2001). Calidad de vida relacionada con la salud en pacientes ancianos en atención primaria. Aten Primaria. 28. 167-173
  • Prieto, L, Prieto, L, Badía, X. (2001). Cuestionarios de salud: concepto y metodología. Aten Primaria. 28. 201-209
  • Blanco-Rivera, MC. (2005). Calidad de vida en pacientes tratados de melanoma de coroides. Universidad de Santiago de Compostela. Santiago de Compostela.
  • Linder, M, Chang, TS, Scott, IU, Hay, D, Chambers, K, Sibley, LM. (1999). Validity of the visual function index (VF-14) in patients with retinal disease. Arch Ophthalmol. 117. 1611-1616
  • Melia, BM, Abramson, DH, Albert, DM, Boldt, HC, Earle, JD, Hanson, WF. (2001). Collaborative Ocular Melanoma Study (COMS) randomized trial of I-125 brachytherapy for medium choroidal melanoma, I: Visual acuity after 3 years COMS report no. 16. Ophthalmology. 108. 348-366
  • Shields, CL, Shields, JA, Carter, J, Gündüz, K, Miyamoto, C, Micaily, B. (2000). Plaque radiotherapy for uveal melanoma: long-term visual outcome in 1106 consecutive patients. Arch Ophthalmol. 118. 1219-1228
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