Nanocarriers for enhancing the performance of immunomodulatory molecules

  1. Olivera Fernández, Ana
Dirixida por:
  1. Dolores Torres López Director
  2. María José Alonso Fernández Director

Universidade de defensa: Universidade de Santiago de Compostela

Fecha de defensa: 13 de outubro de 2020

Tribunal:
  1. Felipe García Alcaide Presidente/a
  2. Carlos Diéguez González Secretario
  3. Maria Marlow Vogal

Tipo: Tese

Teseo: 637210 DIALNET lock_openMINERVA editor

Resumo

Nanotechnology offers the possibility of enhancing the performance of immunomodulatory molecules by facilitating their transport across biological barriers and targeting them to the immune system. Considering this promising potential, this thesis has focused on the development of polymeric nanocarriers loaded with an immunomodulatory molecule for the prevention of type 1 diabetes. Furthermore, pursuing the transdermal supplementation of this molecule, these nanocarriers were optimized to enhance its penetration across the skin.