Marcadores moleculares en el cáncer de mama. Implicaciones terapéuticas

  1. Cebey López, V. 1
  2. Álvarez Fernández, J. 1
  3. Palacios Ozores, P. 1
  4. Cortegoso Mosquera, A. 1
  5. López López, R. 1
  1. 1 Servicio de Oncología Médica y Grupo de Oncología Médica Traslacional, Hospital Clínico Universitario e Instituto de Investigación Sanitaria-CIBERONC, Santiago de Compostela, La Coruña, España
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Ano de publicación: 2021

Título do exemplar: Enfermedades oncológicas (IV)Melanoma, cáncer de mama y tumores ginecológicos

Serie: 13

Número: 27

Páxinas: 1543-1545

Tipo: Artigo

DOI: 10.1016/J.MED.2021.03.006 DIALNET GOOGLE SCHOLAR

Outras publicacións en: Medicine: Programa de Formación Médica Continuada Acreditado

Obxectivos de Desenvolvemento Sustentable

Resumo

Breast cancer is one of the tumor types in which the use of biomarkers has been earlier incorporated into clinical practice and in the greatest number. Biomarkers are classified into two groups: prognostic markers and predictive response markers, but some of them belong to both groups. Biomarkers, including immunohistochemistry markers (like estrogen, progesterone receptors, HER2 and Ki67) and current ones based mainly on gene (BRCA, PI3K) and immune system (PD-L1, TILS) expression, are essential in disease classification and treatment choice. Nowadays, molecular and liquid-biopsy platforms, are being validated.

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Fonte de datos: Dialnet