Varón de 61 años con deterioro cognitivo subagudo y ataxia de la marcha
- A. González Noya
- A.M. Lorenzo Vizcaya
- Raquel Fernández González
- D. Rodríguez Gómez
ISSN: 0304-4866, 1989-3922
Year of publication: 2019
Volume: 80
Issue: 1
Pages: 12-13
Type: Article
More publications in: Galicia Clínica
Abstract
Creutzfeldt-Jakob disease (CJD) is the most frequent of the human prion diseases, although it is still rare. The typical presentation is the presence of dementia and myoclonus, in young patients; with a rapid disease progression and high early mortality. While brain biopsy is the gold standard test for diagnosis, it is often unnecessary. A typical clinical presentation with corroborating findings on magnetic resonance imaging, electroencephalography, and cerebrospinal fluid are in most cases sufficient to exclude other causes and establish CJD as the probable diagnosis.