Espectro clínico de la Enfermedad de Castleman

  1. Guzmán Fernández, María Rebeca
  2. Campoy García, Fiz
  3. Pereiro Sánchez, María
  4. Sastre Moral, José Luis
Journal:
Galicia Clínica

ISSN: 0304-4866 1989-3922

Year of publication: 2014

Volume: 75

Issue: 4

Pages: 191-194

Type: Article

DOI: 10.22546/30/569 DIALNET GOOGLE SCHOLAR lock_openDialnet editor

More publications in: Galicia Clínica

Sustainable development goals

Abstract

Castleman�s disease (CD) is a rare hematological disease characterized by hyperplasia of lymphoid nodules with two distinct histological and clinical patterns: hyaline - vascular which is usually single-center, low and aggressive behavior which gets exeresis healing in most of cases. The plasma cell variant is more aggressive clinical presentation mimics highgrade lymphomas and requires chemotherapy to eradicate. Play an etiopathogenic role HHV -8 and IL -6 and IL -1 cytokines. New drugs based on the blockade of IL -6 or its receptors have recently proved useful in the control of the disease. We present cases representing the spectrum of CD.