Eficiencia de un tratamiento de duración fija con Venetoclax en combinación con Rituximab en pacientes con Leucemia Linfocítica Crónica (LLC)
- Raúl Ferrando 1
- Eduardo Ríos 2
- José Luis Sastre 3
- Áurea Gómez 3
- María Echave 4
- Manuel Gómez Barrera 4
- Itziar Oyagüez 4
- Julia Salvador 5
- Raquel Sánchez 5
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1
Hospital General de Castellón
info
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2
Hospital Universitario de Valme
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- 3 Hospital Universitario de Ourense
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4
Pharmacoeconomics and Outcomes Research Iberia
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Pharmacoeconomics and Outcomes Research Iberia
Pozuelo de Alarcón, España
- 5 AbbVie Spain
ISSN: 1698-4277
Ano de publicación: 2021
Volume: 19
Número: 2
Páxinas: 78-87
Tipo: Artigo
Outras publicacións en: Actualidad en farmacología y terapéutica
Resumo
This work presents a review on the efficiency of a fixed-duration treatment with venetoclax (BCL-2 inhibitor) in combination with rituximab, as therapy for patients with chronic lymphocytic leukemia. Venetoclax in combination with rituximab has shown high response rates and minimal residual disease in patients with relapsed or refractory chronic lymphocytic leukemia; the fixed duration of venetoclax in combination makes it also in a predictable cost option that generates savings versus alternatives to progression, contributing thus to the sustainability of the health system.