Hemoglobina glicosilada y su relación con la fracción de eyección del ventrículo izquierdo en pacientes diabéticos tipo 2 y un primer infarto agudo de miocardio

  1. Pérez Mayorga, Maritza 1
  2. Gómez Arbelaez, Diego 2
  3. Melgarejo, Enrique 1
  4. Bravo, María Alejandra 1
  5. Martínez, Azucena 1
  6. Artemo González, Luis 1
  7. López Jaramillo, Patricio 2
  1. 1 Universidad Militar Nueva Granada
    info

    Universidad Militar Nueva Granada

    Bogotá, Colombia

    ROR https://ror.org/05n0gsn30

  2. 2 Universidad de Santander
Revista:
Revista Med de la Facultad de Medicina

ISSN: 1909-7700,  0121-5256

Ano de publicación: 2014

Volume: 22

Número: 2

Tipo: Artigo

DOI: 10.18359/RMED.1165 DIALNET GOOGLE SCHOLAR lock_openDialnet editor

Outras publicacións en: Revista Med de la Facultad de Medicina

Obxectivos de Desenvolvemento Sustentable

Resumo

Dentro del espectro de las enfermedades cardiovasculares, la enfermedad isquémica del corazón se encuentra dentro de las dos patologías con mayor tasa de discapacidad y mortalidad. La Diabetes Mellitus tipo 2 es uno de los factores asociados a peor pronóstico en sujetos con esta enfermedad. Hoy en día se conoce que sobre el miocardio en isquemia, la hiperglicemia aumenta el estrés oxidativo, la hipoxia y por ende su necrosis. Objetivo: Establecer si existe una relación entre los niveles de hemoglobina glicosilada de pacientes diabéticos tipo 2 con un primer infarto agudo de miocardio y la función del ventrículo izquierdo intrahospitalaria, medida por la fracción de eyección. Materiales y Métodos: Estudio observacional en el que se realizó la caracterización de 36 pacientes con diabetes mellitus tipo 2 y un primer episodio de IAM hospitalizados en el Hospital Militar Central. Resultados: Con el test de exactitud de Fischer se obtuvo que los pacientes diabéticos tipo 2 con primer infarto agudo de miocardio y valores de hemoglobina glicosilada por encima de 8,5% presentaron una tendencia a tener fracciones de eyección por debajo de 50% (P= 0,019). Conclusiones: Se necesitan más estudios en los que se evalúen poblaciones más grandes de pacientes para lograr representar todo el espectro de valores de hemoglobina glicosilada y con ello, establecer un punto de corte más exacto a partir del cual sea válido sospechar una disminución de la función ventricular izquierda en el escenario de diabetes mellitus tipo 2 y un primer infarto agudo de miocardio.

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Fonte de datos: Dialnet