Terminal Carboxylate Effects on the Thermodynamics and Kinetics of Cucurbit[7]uril Binding to Guests Containing a Central Bis(Pyridinium)-Xylylene Site

  1. Neira, Iago 1
  2. Garcia, Marcos D. 2
  3. Peinador, Carlos 2
  4. Kaifer, Angel 1
  1. 1 University of Miami
    info

    University of Miami

    Coral Gables, Estados Unidos

    ROR https://ror.org/02dgjyy92

  2. 2 Universidade da Coruña
    info

    Universidade da Coruña

    La Coruña, España

    ROR https://ror.org/01qckj285

Editor: SupraBank

Ano de publicación: 2024

Tipo: Dataset

CC BY-SA 4.0

DOI: 10.34804/SUPRA.20210928220 lock_openAcceso aberto editor

Resumo

A series of bis(pyridinium)-xylylene derivatives bearing carboxylate terminal groups were investigated as guests for the cucurbit[7]uril host in aqueous solution. While the presence of the terminal carboxylates has a modest effect on the thermodynamic stability of the complexes, the kinetics of complex association/dissociation is strongly affected. The relative position (meta, para) of the carboxylate group in relation to the pyridinium nitrogen also exerts a considerable effect on the binding kinetics.