Lara
García Varela
University of Groningen
Groninga, HolandaPublications in collaboration with researchers from University of Groningen (10)
2022
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Dose-response assessment of cerebral P-glycoprotein inhibition in vivo with [18F]MC225 and PET
Journal of Controlled Release, Vol. 347, pp. 500-507
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Impact of an Adenosine A2AReceptor Agonist and Antagonist on Binding of the Dopamine D2Receptor Ligand [11C]raclopride in the Rodent Striatum
Molecular Pharmaceutics, Vol. 19, Núm. 8, pp. 2992-3001
2021
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A new approach to produce [18F]MC225 via one-step synthesis, a PET radiotracer for measuring P-gp function
EJNMMI Radiopharmacy and Chemistry, Vol. 6, Núm. 1
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Evaluation of P-glycoprotein function at the blood–brain barrier using [18F]MC225-PET
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 48, Núm. 12, pp. 4105-4106
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Head-to-head comparison of (R)-[11C]verapamil and [18F]MC225 in non-human primates, tracers for measuring P-glycoprotein function
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 48, Núm. 13, pp. 4307-4317
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In Vivo Induction of P-Glycoprotein Function can be Measured with [18F]MC225 and PET
Molecular Pharmaceutics, Vol. 18, Núm. 8, pp. 3073-3085
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Pharmacokinetic Modeling of (R)-[11C]verapamil to Measure the P-Glycoprotein Function in Nonhuman Primates
Molecular Pharmaceutics, Vol. 18, Núm. 1, pp. 416-428
2020
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PET imaging of ABC transporters at the blood-brain barrier
PET and SPECT of Neurobiological Systems (Springer International Publishing), pp. 809-850
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Pharmacokinetic Modeling of [18F]MC225 for Quantification of the P-Glycoprotein Function at the Blood-Brain Barrier in Non-Human Primates with PET
Molecular Pharmaceutics, Vol. 17, Núm. 9, pp. 3477-3486
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Test-Retest Repeatability of [18F]MC225-PET in Rodents: A Tracer for Imaging of P-gp Function
ACS Chemical Neuroscience, Vol. 11, Núm. 4, pp. 648-658