Publications by the researcher in collaboration with Enrique Raviña Rubira (32)

2017

  1. 3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation

    ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933

2014

  1. Synthesis and biological evaluation of a series of aminoalkyl-tetralones and tetralols as dual dopamine/serotonin ligands

    European Journal of Medicinal Chemistry, Vol. 71, pp. 237-249

2011

  1. Potential atypical antipsychotics: Synthesis, binding affinity and SAR of new heterocyclic bioisosteric butyrophenone analogues as multitarget ligands

    MedChemComm, Vol. 2, Núm. 12, pp. 1194-1200

2009

  1. Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif

    Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 21, pp. 6059-6062

  2. Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands

    Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 6, pp. 1773-1778

2008

  1. 1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 6, pp. 2852-2869

  2. Corrigendum to "1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor" [Bioorg. Med. Chem. 16 (2008) 2852-2869] (DOI:10.1016/j.bmc.2008.01.002)

    Bioorganic and Medicinal Chemistry

  3. Synthesis, adenosine receptor binding and 3D-QSAR of 4-substituted 2-(2′-furyl)-1,2,4-triazolo[1,5-a]quinoxalines

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 4, pp. 2103-2113

  4. Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics

    Journal of Medicinal Chemistry, Vol. 51, Núm. 19, pp. 6085-6094

2007

  1. Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor

    Journal of Medicinal Chemistry, Vol. 50, Núm. 14, pp. 3242-3255

  2. Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 17, pp. 4873-4877

2006

  1. Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor

    Journal of Medicinal Chemistry, Vol. 49, Núm. 1, pp. 282-299

  2. QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine

    Neuropharmacology, Vol. 51, Núm. 2, pp. 251-262

2005

  1. Synthesis and binding affinity of novel 3-aminoethyl-1-tetralones, potential atypical antipsychotics

    Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 12, pp. 3063-3066

2004

  1. 8-Substituted-9-deazaxanthines as adenosine receptor ligands: Design, synthesis and structure-affinity relationships at A 2B

    European Journal of Medicinal Chemistry, Vol. 39, Núm. 10, pp. 879-887

  2. Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics

    Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 3, pp. 585-589

2003

  1. Conformationally constrained butyrophenones as new pharmacological tools to study 5-HT2A and 5-HT2C receptor behaviours

    European Journal of Medicinal Chemistry

  2. In vivo and in vitro pharmacological studies of a new hypotensive compound (QF0301B) in rat: Comparison with prazosin, a known α1- adrenoceptor antagonist

    Vascular Pharmacology, Vol. 40, Núm. 2, pp. 97-108

2002

  1. New serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonists: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones

    Journal of Medicinal Chemistry, Vol. 45, Núm. 1, pp. 54-71

2000

  1. Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: Synthesis and determination of affinities at D2, 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors

    European Journal of Medicinal Chemistry, Vol. 35, Núm. 1, pp. 83-95